BDBM11242 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide::med.21724, Compound 76::niclosamide

SMILES Oc1ccc(Cl)cc1C(=O)Nc1ccc(cc1Cl)[N+]([O-])=O

InChI Key InChIKey=RJMUSRYZPJIFPJ-UHFFFAOYSA-N

Data  31 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11242   

TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM11242(5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...)
Affinity DataIC50:  250nMAssay Description:Inhibition of STAT3 in human HeLa cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM11242(5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...)
Affinity DataIC50:  210nMAssay Description:Inhibition of STAT3 phosphorylation in human MDA-MB-231 cells by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM11242(5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...)
Affinity DataIC50:  1.93E+3nMAssay Description:Inhibition of human recombinant STAT3 assessed as reduction in DNA binding activity with HepG2 nuclear extract incubated for 1 hr by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed